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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42374Generated: October 25, 2026

N'-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazide → HCID 67093792, compound

https://huagongshe.com/reaction/42374

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN'-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazideHCID 67094058—
SolventAcetic AcidHCID 176—
ProductHCID 67093792HCID 67093792—

Reaction Conditions

Temperature180 °C

Reaction Steps

A mixture of N′-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazide (7-3) (70 mg, 0.227 mmol) in AcOH (5 mL) was heated under microwave irradiation at 180° C. for 15 minutes. The solvent was removed under reduced pressure to give 1-ethyl-8-phenyl[1,2,4]triazolo[4,3-a]-1,5-naphthyridin-7(6H)-one (7-4) as pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536193B2
Source datasetuspto-grants-2013_09
ORD IDord-e9822ebf9b684921a07ed6fcd74abb35
Source noteuspto-grants-2013_09