HCID 11265111, compound → HCID 11845933, compound

HRID 424379Notes

Reaction equation

HRID 424379 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][O:10]COC.Cl[C:15]1[CH:16]=[C:17]([B:21]2C3C=CC(F)=CC=3CO2)[CH:18]=[CH:19][CH:20]=1>>[C:17]1([B:21]2[C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[CH2:8][CH2:9][O:10]2)[CH:18]=[CH:19][CH:20]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 11265111HCID 11265111, compoundHCID 17863604HCID 17863604, compound

Product 1

HCID 11845933HCID 11845933, compound

Procedure

This compound was synthesized from 22b and 7a in a similar manner to compound 9f: colorless oil; 1H NMR (300 MHz, DMSO-d6) δ (ppm) 2.94 (t, J=5.9 Hz, 2H), 4.21 (t, J=5.9 Hz, 2H), 7.28 (t, J=7.9 Hz, 2H), 7.3-7.5 (m, 4H), 7.66 (d, J=7.0 Hz, 1H), 7.75 (d, J=7.6 Hz, 2H); ESI-MS m/z not observed; HPLC purity 96.0%; Anal (C14H13BO) C. H.

Sources & evidence

ORD record
ord-a5ff81b315904158bc94eada4c88d725
Source dataset
uspto-grants-2012_01
Patent number
US08106031B2

Reaction notes

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