Water → HCID 21022065, compound

HRID 424623Notes

Reaction equation

HRID 424623 reaction equation
[CH3:1][NH2:2].[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([Cl:11])[C:5]=1[S:12](Cl)(=[O:14])=[O:13].O>O1CCOCC1>[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([Cl:11])[C:5]=1[S:12]([NH:2][CH3:1])(=[O:14])=[O:13]

Participants

5

Reactant 3

HCID 962WaterHCID 6329MethylamineHCID 5213352,4,6-Trichlorobenzenesulfonyl chloride

Product 1

HCID 21022065HCID 21022065, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

40% strength aq. methylamine soln. (36.0 g, 464 mmol) was added dropwise to a soln. of 2,4,6-trichorobenzenesulfonic acid chloride (10.0 g, 35.7 mmol) in 1,4-dioxane (60 ml) and the mixture was stirred at RT for 30 min. Water (500 ml) was then added, with vigorous stirring, whereupon a white precipitate formed, which was filtered out and dried over potassium hydroxide in a desiccator.

Workup

  1. addition(36.0 g, 464 mmol) was added dropwise to a soln
  2. customformed
  3. filtrationwhich was filtered out
  4. dry with materialdried over potassium hydroxide in a desiccator

Sources & evidence

ORD record
ord-f9336cd561964fa49964c9a13626ae06
Source dataset
uspto-grants-2012_01
Patent number
US08106055B2

Reaction notes

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