Hydrochloric Acid → (S)-N,N-DiMethyl-2-pyrrolidinecarboxaMide HCl

HRID 424661Notes

Reaction equation

HRID 424661 reaction equation
C(OC([N:8]1[CH2:17][CH2:16][CH2:15][C@H:9]1[C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=O)(C)(C)C.[ClH:18]>>[ClH:18].[CH3:13][N:12]([CH3:14])[C:10](=[O:11])[C@@H:9]1[CH2:15][CH2:16][CH2:17][NH:8]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10354388HCID 10354388, compound

Product 1

HCID 66702040(S)-N,N-DiMethyl-2-pyrrolidinecarboxaMide HCl

Procedure

To the subtitle product of step i) (5.0 g) was added hydrochloric acid (20 ml, 4M). The mixture was stirred at room temperature for 3 h before the solvent was evaporated to afford the subtitle compound as a colourless solid. Yield: 3.50 g

Workup

  1. customwas evaporated

Sources & evidence

ORD record
ord-c6ab725a1dc04a6187594ecd46a41378
Source dataset
uspto-grants-2012_01
Patent number
US08106063B2

Reaction notes

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