Thionyl Chloride → HCID 86629254, compound

Participants

Reaction Steps

To thionyl chloride (1.5 mL, 20 mmol) is added 2′-bromo-4′-[3-(2,6-dichloro-phenyl)-5-isopropyl-3H-[1,2,3]triazol-4-ylmethoxy]-biphenyl-4-carboxylic acid (0.074 g, 0.13 mmol). The reaction is stirred overnight at room temperature. The reaction mixture is concentrated under reduced pressure to give 2′-Bromo-4′-[3-(2,6-dichloro-phenyl)-5-isopropyl-3H-[1,2,3]triazol-4-ylmethoxy]-biphenyl-4-carbonyl chloride.

Provenance & Evidence