Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 181371-35-7 | HCID 341367 | — |
| Reactant | Methyl 3,3,3-trifluoro-2-oxopropanoate | HCID 2734931 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 44139821 | HCID 44139821 | — |
Reaction Steps
To a chloroform solution (5 ml) of 1-(4-fluorophenyl)-3-methyl-5-pyrazolone (96 mg, 0.5 mmol), methyl trifluoropyruvate (78 mg, 0.5 mmol) was added at room temperature and the mixture was stirred at 80° C. for 2 hours. After removing the solvent under reduced pressure, the title compound was obtained as a pale yellow solid (174 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08106086B2 |
|---|
| Source dataset | uspto-grants-2012_01 |
|---|
| ORD ID | ord-2b822508d1324e449b384552c40b3c11 |
|---|
| Source note | uspto-grants-2012_01 |
|---|
