Methyl 3,3,3-trifluoro-2-oxopropanoate → HCID 44139823, compound

Participants

Reaction Conditions

Reaction Steps

To a chloroform solution (5 ml) of 3-methyl-1-(4-methylphenyl)-5-pyrazolone (94 mg, 0.5 mmol), methyl trifluoropyruvate (78 mg, 0.5 mmol) was added at room temperature and the mixture was stirred at 80° C. for 2 hours. After removing the solvent under reduced pressure, the title compound was obtained as a pale yellow solid (172 mg).

Provenance & Evidence