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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425011Generated: October 31, 2026

1,2,3,4-Tetrahydroisoquinoline → HCID 66703603, compound

https://huagongshe.com/reaction/425011

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-TetrahydroisoquinolineHCID 7046—
ReactantHCID 59786775HCID 59786775—
ProductHCID 66703603HCID 66703603—

Reaction Steps

Using general procedure 1 and purification method D with [(1R)-1-{(2R)-oxiran-2-yl}-2-(2,5-difluoro-phenyl)-ethyl]carbamic acid tert-butylester (0.385 g, 1.3 mmol) and 1,2,3,4,-tetrahydro-isoquinoline (0.200 mL, 1.50 mmol) gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106090B2
Source datasetuspto-grants-2012_01
ORD IDord-217cd3d8b0614f269228bc6ea10c2b13
Source noteuspto-grants-2012_01