3-Hydroxybenzaldehyde → 1-[2-Hydroxy-4-carboxydimethylmethyloxyphenyl]-3-[3-hydroxyphenyl]prop-2-en-1-one

HRID 425116Notes

Reaction equation

HRID 425116 reaction equation
[OH:1][C:2]1[C:7]([O:8][CH3:9])=[C:6]([C:10]([O:12]CC)=[O:11])[C:5]([CH3:15])=[C:4]([CH3:16])[C:3]=1[C:17](=[O:35])[CH:18]=[CH:19][C:20]1[CH:25]=[C:24](C(C)(C)C)[C:23](O)=[C:22](C(C)(C)C)[CH:21]=1.[OH:36]C1C=C(C=CC=1)C=O>>[OH:1][C:2]1[C:7]([O:8][CH3:9])=[C:6]([C:10]([OH:12])=[O:11])[C:5]([CH3:15])=[C:4]([CH3:16])[C:3]=1[C:17](=[O:35])[CH:18]=[CH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([OH:36])[CH:21]=1

Participants

3

Reactant 2

HCID 1013-HydroxybenzaldehydeHCID 865999731-[2-Hydroxy-4-ethoxycarbonyldimethylmethyloxyphenyl]-3-[3,5-ditertbutyl-4-hydroxyphenyl] prop-2-en-1-one2×

Product 1

HCID 865999761-[2-Hydroxy-4-carboxydimethylmethyloxyphenyl]-3-[3-hydroxyphenyl]prop-2-en-1-one

Procedure

This compound was synthesized from 2′-hydroxy-4′-ethyloxycarbonyl dimethylmethyloxyacetophenone (starting material 1) and 3-hydroxybenzaldehyde according to general method 2 described earlier.

Sources & evidence

ORD record
ord-72a7dd20ccb947d2bfb4014d8cb49b1b
Source dataset
uspto-grants-2012_01
Patent number
US08106097B2

Reaction notes

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