HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methylimidazo[2,1-B][1,3]thiazole-5-carboxylic acid → (1S,2S,5R)-2-{[6-Methyl-(imidazo[2,1-b]thiazole-5-carbonyl)-amino]-methyl}-7-methyl-3-aza-bicyclo[3.3.0]octane-3-carboxylic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methylimidazo[2,1-B][1,3]thiazole-5-carboxylic acid | HCID 329979 | — |
| Reactant | (1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]-octane-3-carboxylic acid tert.-butyl ester | HCID 59411604 | — |
| Product | (1S,2S,5R)-2-{[6-Methyl-(imidazo[2,1-b]thiazole-5-carbonyl)-amino]-methyl}-7-methyl-3-aza-bicyclo[3.3.0]octane-3-carboxylic acid tert.-butyl ester | HCID 59411634 | — |
Reaction Steps
prepared by reaction of (1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]-octane-3-carboxylic acid tert.-butyl ester with commercially available 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106215B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-f7b0212d584b469c98d70d25bb4cd4d4 |
| Source note | uspto-grants-2012_01 |