HCID 12362975, compound → (2r,3s)-3-Phenylisoserine amide dibenzoyl-tartaric acid salt

Participants

Reaction Steps

Racemic threo 3-phenylisoserine amide (IX) (120.0 g, 0.67 mole) and (−)-dibenzoyltartaric acid (240.1 g, 0.67 mole) were suspended in ethanol (1080.0 g). The suspension was refluxed for 2 hours, then cooled to room temperature and stirred for further 60 minutes. The product was filtered off, washed with ethanol (400.0 g) and vacuum dried at 50° C. Yield: 180.6 g (0.34 mole, 50%).

Provenance & Evidence