反应详情

4-Chloro-2-(cyclopentylamino)benzonitrile and concentrated sulfuric acid were added to water, followed by stirring while heating under reflux. The reaction liquid was neutralized by adding sodium hydroxide to the reaction liquid, and the organic layer was extracted with chloroform to obtain 4-chloro-2-(cyclopentylamino)benzoic acid.

1. temperaturewhile heating
2. temperatureunder reflux
3. customThe reaction liquid
4. customto the reaction liquid
5. extractionthe organic layer was extracted with chloroform