HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 4-Chloro-2-(cyclopentylamino)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Chloro-2-(cyclopentylamino)benzonitrile | HCID 43681510 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Chloro-2-(cyclopentylamino)benzoic acid | HCID 63081476 | — |
Reaction Steps
4-Chloro-2-(cyclopentylamino)benzonitrile and concentrated sulfuric acid were added to water, followed by stirring while heating under reflux. The reaction liquid was neutralized by adding sodium hydroxide to the reaction liquid, and the organic layer was extracted with chloroform to obtain 4-chloro-2-(cyclopentylamino)benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106190B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-fcc97365de3b4e75b2a6fce892542172 |
| Source note | uspto-grants-2012_01 |