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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425967Generated: October 30, 2026

Sodium Hydroxide → 5-Chloro-2-(cyclohexylamino)benzoic acid

https://huagongshe.com/reaction/425967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantMethyl 5-chloro-2-(cyclohexylamino)benzoateHCID 12329834—
SolventEthanolHCID 702—
Product5-Chloro-2-(cyclohexylamino)benzoic acidHCID 12329833—

Reaction Conditions

Temperature70 °C

Reaction Steps

Methyl 5-chloro-2-(cyclohexylamino)benzoate was dissolved in ethanol, a 1 M sodium hydroxide aqueous solution was added, followed by stirring at 70° C. By post-treating the reaction liquid, 5-chloro-2-(cyclohexylamino)benzoic acid was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106190B2
Source datasetuspto-grants-2012_01
ORD IDord-d841805acea54491801abcd36fb460c1
Source noteuspto-grants-2012_01