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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425980Generated: October 30, 2026

1,2-Dichloroethane → HCID 66703589, compound

https://huagongshe.com/reaction/425980

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantChlorosuccinimideHCID 31398—
ReactantHCID 28330451HCID 28330451—
SolventDimethylformamideHCID 6228—
ProductHCID 66703589HCID 66703589—

Reaction Steps

1-Chloro-2,5-pyrrolidinedione was added at room temperature to a 1,2-dichloroethane and DMF solution of 2-[(cyclopropylmethyl)amino]nicotinic acid, followed by stirring for 1 day. By post-treating the reaction liquid, 5-chloro-2-[(cyclopropylmethyl)amino]nicotinic acid was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106190B2
Source datasetuspto-grants-2012_01
ORD IDord-0b22ba31ead1410392153aab8721010f
Source noteuspto-grants-2012_01