HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 57867958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | HCID 7169935 | HCID 7169935 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57867958 | HCID 57867958 | — |
Reaction Steps
1-[(tert-Butoxycarbonyl)amino]cyclohexancarboxylate, pyrrolidine, 1-ethyl-3-[3-(N,N-dimethylamino)propyl]carbodiimide hydrochloride and 1-hydroxybenzotriazole were allowed to undergo the reaction at room temperature in methylene chloride. By post-treating the reaction liquid, tert-butyl [1-(pyrrolidin-1-ylcarbonyl)cyclohexyl]carbamate was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106190B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-d6073781b4c145c988f32fadc54773fa |
| Source note | uspto-grants-2012_01 |