Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 426001Generated: November 1, 2026

Pyridine → HCID 15851621, compound

https://huagongshe.com/reaction/426001

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantTrifluoroacetic anhydrideHCID 9845—
ReactantHCID 57614568HCID 57614568—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 15851621HCID 15851621—

Reaction Steps

Pyridine and trifluoroacetic anhydride were added to a dioxane solution of 4-tert-butyl-2-fluorobenzamide and stirred at room temperature for 3 hours. By post-treating the reaction liquid, 4-tert-butyl-2-fluorobenzonitrile was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106190B2
Source datasetuspto-grants-2012_01
ORD IDord-7254907d12dc45c6958d77ac282f314e
Source noteuspto-grants-2012_01