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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42623Generated: October 26, 2026

Acetyl chloride → N-[6-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]acetamide

https://huagongshe.com/reaction/42623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantHCID 178503413HCID 178503413—
ProductN-[6-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]acetamideHCID 68444211—

Reaction Steps

Following a similar procedure to that described in example 245, but starting from 3-amino-6-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)pyrazolo[3,4-b]pyridine (obtained in example 180) and acetyl chloride, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536194B2
Source datasetuspto-grants-2013_09
ORD IDord-3c45a0333043499fb2de6436f2dd333b
Source noteuspto-grants-2013_09