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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 426353Generated: November 1, 2026

3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile → HCID 59004817, compound

https://huagongshe.com/reaction/426353

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrileHCID 46738194—
ReactantHCID 59004769HCID 59004769—
ProductHCID 59004817HCID 5900481721%

Reaction Steps

The title compound was prepared in 21% yield from 4-methyl-2-(5-trifluoromethanesulfonyloxy-4′-trifluoromethyl-biphenyl-3-yl)-pentanoic acid methyl ester (prepared in Example 26, step (f)) and 3-fluoro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile under the conditions described in Example 26, step (d).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106236B2
Source datasetuspto-grants-2012_01
ORD IDord-aa1e000b675b47ccb624c68030edf483
Source noteuspto-grants-2012_01