Methyl 2-bromopropionate → HCID 20390830, compound

HRID 426436Notes

Reaction equation

HRID 426436 reaction equation
[Na].[Cl:2][C:3]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:4]=1[O:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1.Br[CH:20]([CH3:25])[C:21]([O:23][CH3:24])=[O:22]>C(O)C>[Cl:2][C:3]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:4]=1[O:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][CH:20]([CH3:25])[C:21]([O:23][CH3:24])=[O:22])=[CH:11][CH:12]=1

Participants

5

Reactant 3

HCID 95576Methyl 2-bromopropionateHCID 5360545SodiumHCID 141192784-[(2,4-Dichlorophenoxy)methyl]phenol

Product 1

HCID 20390830HCID 20390830, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.3 gm of sodium were dissolved in 100 ml of absolute ethanol, 26.9 gm of 4-(2,4-dichlorophenoxy-methyl)-phenol and 16.7 gm of methyl 2-bromo-propionate were added to the solution, and the mixture was boiled for 3 hours. Thereafter, the reaction solution was evaporated, and the residue was worked up as usual with water and chloroform, yielding 80% of theory of the desired compound named in the heading, which had a melting point of 64° C.

Workup

  1. customThereafter, the reaction solution was evaporated

Sources & evidence

ORD record
ord-30ea12d20bcb4551948406918baaf996
Source dataset
uspto-grants-1979_10
Patent number
US04169720

Reaction notes

Loading…