反应详情

A mixture consisting of 2.2 gm of methyl 2-[4-(4-chlorophenoxy-methyl)-phenoxy]-propionate, 2.4 gm of 2-(2,4,5-trichloro-phenoxy)-ethanol and 0.03 gm of sodium was heated at about 120°-150° C. and a pressure of 150 mm Hg for four hours. After cooling, the reaction mixture was briefly boiled with acetone, the cooled solution was filtered, and the solvent was removed from the filtrate in vacuo. The residue was recrystallized from ethanol/water, yielding 1.3 gm (36% of theory) of the compound of the formula ##STR19## which had a melting point of 83° C.

1. temperaturewas heated at about 120°-150° C.
2. temperatureAfter cooling
3. filtrationthe cooled solution was filtered
4. customthe solvent was removed from the filtrate in vacuo
5. customThe residue was recrystallized from ethanol/water
6. customyielding 1.3 gm (36% of theory) of the compound of the formula ##STR19## which