Oxalyl chloride → HCID 20391273, compound

HRID 426525Notes

Reaction equation

HRID 426525 reaction equation
C[Si](C)(C)[NH:3][C:4]([C:6]1[O:7][CH:8]=[CH:9][CH:10]=1)=[O:5].[C:13](Cl)(=[O:17])[C:14]([Cl:16])=[O:15]>C(Cl)Cl>[O:7]1[CH:8]=[CH:9][CH:10]=[C:6]1[C:4]([NH:3][C:13](=[O:17])[C:14]([Cl:16])=[O:15])=[O:5]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 11701149HCID 11701149, compound

Product 1

HCID 20391273HCID 20391273, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

3.6 g. of N-(trimethylsilyl)-2-furancarboxamide are dissolved in 50 ml. of absolute methylene chloride and the solution is added dropwise at -10° to a solution of 1.8 g. of oxalyl chloride in 100 ml. of methylene chloride. The mixture is stirred for one hour at 0°. After evaporating the solvent, [(2-Furanylcarbonyl)amino]oxoacetyl chloride remains as a yellowish oil which is used for the next reaction without further purification.

Workup

  1. customAfter evaporating the solvent, [(2-Furanylcarbonyl)amino]oxoacetyl chloride
  2. customis used for the next reaction without further purification

Sources & evidence

ORD record
ord-da345bf5fa0a4cf983533ce6ee2208da
Source dataset
uspto-grants-1979_10
Patent number
US04169947

Reaction notes

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