反应详情

375 Grams (1.6 moles) of 1-methyl-3,5-diphenylpyrazole is dissolved in 1850 ml. of dry xylene and heated to 60° C. 208.13 Grams (1.65 moles) of dimethylsulfate in 150 ml. of dry xylene is then added and the temperature of the reaction mixture raised to 105° C. to 110° C. and maintained there for 7.5 hours. The mixture is allowed to cool and then filtered. A brown solid is recovered, washed with xylene and then dry acetone to give the product in 88% yield, having a melting point of 155° C. to 157° C.

1. temperaturethe temperature of the reaction mixture raised to 105° C. to 110° C.
2. temperaturemaintained there for 7.5 hours
3. temperatureto cool
4. filtrationfiltered
5. customA brown solid is recovered
6. washwashed with xylene
7. customdry acetone to give the product in 88% yield