反应详情

温度

175 °C

26.6 parts of the compound ##STR5## (from aniline and N-phenyl maleic imide) are dissolved in 100 ml of o-dichlorobenzene. 11.9 parts of phenylisocyanate are added and the reaction mixture is left to stand overnight. After the addition of 0.1 g of 1,4-diaza-bicyclo-[2,2,2]-octane, the solution is stirred for 6 hours at 175° C., the solvent is distilled off under vacuum and toluene is added to the residue. The crystalline precipitate obtained is suction filtered and recrystallised from ethyl acetate. The structure obtained by calculation is confirmed by the NMR- and IR-spectra (for hydantoin 1715 and 1770 cm-1 ; for amide 1690 cm-1).

1. waitthe reaction mixture is left
2. distillationthe solvent is distilled off under vacuum and toluene
3. additionis added to the residue
4. customThe crystalline precipitate obtained
5. filtrationfiltered
6. customrecrystallised from ethyl acetate
7. customThe structure obtained by calculation