反应详情

A mixture of 6.5 g (0.02 mol) of 1-(2-acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole, 100 ml of 12 N hydrochloric acid and 100 ml of 95% ethanol was refluxed for 4.5 hours. The mixture was evaporated to dryness to give a gummy residue which crystallized upon addition of ethanol to give 1-(2-aminoethyl)-5-(2,4-dinitrophenylthio)-tetrazole hydrochloride, mp 217°-210° (d).

1. temperaturewas refluxed for 4.5 hours
2. customThe mixture was evaporated to dryness
3. customto give a gummy residue which
4. customcrystallized upon addition of ethanol