HCID 70591890, compound → HCID 70592081, compound

HRID 426733Notes

Reaction equation

HRID 426733 reaction equation
[C:1]1([N:7]2[C:11]([C:12]3[N:13]([NH2:17])[CH2:14][CH2:15][N:16]=3)=[CH:10][CH:9]=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>[Rh].CO>[CH:1]1([N:7]2[C:11]([C:12]3[N:13]([NH2:17])[CH2:14][CH2:15][N:16]=3)=[CH:10][CH:9]=[N:8]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 1

HCID 70591890HCID 70591890, compound

Product 1

HCID 70592081HCID 70592081, compound

Reagents, catalysts & solvents 2

HCID 23948RhodiumCatalystHCID 887MethanolSolvent

Procedure

2-(1-phenyl-5-pyrazolyl)-amino-2-imidazoline (9.00 g.) in 250 ml. methanol was hydrogenated at 3 atmospheres and 60° C. over 5% Rh/Al2O3 catalyst. The catalyst was filtered, the solvent removed in vacuum and the residue crystallized from benzene to give 4.0 g. of product, mp 183°-185° C.

Workup

  1. filtrationThe catalyst was filtered
  2. customthe solvent removed in vacuum
  3. customthe residue crystallized from benzene
  4. customto give 4.0 g

Sources & evidence

ORD record
ord-4981e9cdc5bc4aab95dec77a934bcedc
Source dataset
uspto-grants-1979_10
Patent number
US04171367

Reaction notes

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