HCID 53690970, compound → HCID 20389867, compound

HRID 426773Notes

Reaction equation

HRID 426773 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:10][C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[C:6]([CH:9]=1)[CH2:7][OH:8]>C1(C)C=CC=CC=1.[O-2].[Mn+4].[O-2]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:10][C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[C:6]([CH:9]=1)[CH:7]=[O:8]

Participants

4

Reactant 1

HCID 53690970HCID 53690970, compound

Product 1

HCID 20389867HCID 20389867, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 1140TolueneSolvent

Procedure

To a solution of 51.4 g (0.2 mole) of 5-chloro-2-(2-thienylthio)-benzyl alcohol in 400 ml of toluene is added 173.9 g (2.0 mole) of manganese (IV)-oxide, and stirring is maintained at 20°-25° for 25 hours. The precipitate is then filtered off with suction, and the filtrate is concentrated in vacuo to yield 5-chloro-2-(2-thienylthio)-benzaldehyde as yellow oil.

Workup

  1. temperatureis maintained at 20°-25° for 25 hours
  2. filtrationThe precipitate is then filtered off with suction
  3. concentrationthe filtrate is concentrated in vacuo

Sources & evidence

ORD record
ord-8dead94e0a3247e3b1dcb351eebc7b3f
Source dataset
uspto-grants-1979_10
Patent number
US04171366

Reaction notes

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