Sodium Hydroxide → HCID 20390079, compound

Participants

Reaction Steps

2.9 gms. of DL-α-[[(methylthio)methyl]thio]benzene acetic acid, (methylthio)methyl ester are dissolved in 10 ml. of ethanol. 20 ml. of 1 N alcoholic sodium hydroxide solution are added and the mixture is permitted to stand overnight. This is then concentrated, the residue is dissolved in water, the aqueous solution is extracted once with ether, then acidificed and the oil is extracted with ether. After drying with magnesium sulfate and evaporating the solvent 1.8 gms. of DL-α-[[(methylthio)methyl]thio]benzeneacetic acid are obtained as an oil.

Provenance & Evidence