Sodium Hydroxide → HCID 70611106, compound

HRID 426943Notes

Reaction equation

HRID 426943 reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])[C:4]([N+:12]([O-:14])=[O:13])=[N:3]1.[OH-].[Na+:16].[Na]>>[CH3:1][N:2]1[CH:6]=[C:5]([CH:7]=[CH:8][C:9]([O-:11])=[O:10])[C:4]([N+:12]([O-:14])=[O:13])=[N:3]1.[Na+:16]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 5360545SodiumHCID 543730603-(1-Methyl-3-nitro-1H-pyrazol-4-yl)prop-2-enoic acid

Product 1

HCID 70611106HCID 70611106, compound

Procedure

197 mg. 3-(1-methyl-3-nitro-4-pyrazolyl)-acrylic acid (prepared according to Example 1) are neutralized with a dilute aqueous solution of sodium hydroxide. The clear solution is evaporated to dryness and the residue is triturated with isopropanol. After filtering off with suction and washing with diethyl ether, there are obtained 170 mg. of the desired sodium salt; m.p. 306° (with foaming).

Workup

  1. customThe clear solution is evaporated to dryness
  2. customthe residue is triturated with isopropanol
  3. filtrationAfter filtering off with suction
  4. washwashing with diethyl ether, there
  5. customare obtained 170 mg

Sources & evidence

ORD record
ord-1ba0a0919a114a2ea66a9c5755a52441
Source dataset
uspto-grants-1979_10
Patent number
US04172136

Reaction notes

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