HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Amino-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid → 7-Aminocephalosporanic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Amino-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid | HCID 12942034 | — |
| Reactant | 2-Pyridylsulfinylacetic acid | HCID 20297199 | — |
| Product | 7-Aminocephalosporanic acid | HCID 441328 | — |
| Product | 7-(2-Pyridylsulfinylacetamido)-3-(2-methyl-1,3,4-thiadiazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid | HCID 131711648 | — |
Reaction Steps
Procedures of Example 10 were repeated by using 2-pyridylsulfinylacetic acid and 7-amino-3-(2-methyl-1,3,4-thiadiazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid instead of the 4-pyridylsulfinylacetic acid and the 7-aminocephalosporanic acid respectively to obtain 7-(2-pyridylsulfinylacetamido)-3-(2-methyl-1,3,4-thiadiazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid of the R form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04172197 |
| Source dataset | uspto-grants-1979_10 |
| ORD ID | ord-531c6074c9d1415fa30f9eab410931fe |
| Source note | uspto-grants-1979_10 |