Dicyclohexylcarbodiimide → {{8-[5-(4-Fluorophenyl)-2-pentyl]-5,5-dimethyl-10-(4-morpholinobutyryloxy)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridin-2-yl}acetyl}urea hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	Dicyclohexylcarbodiimide	HCID 10868	—
Reactant	4-Morpholin-4-Yl-Butyric Acid Hydrochloride	HCID 12733746	—
Reactant	{{8-[5-(4-Fluorophenyl)-2-pentyl]-10-hydroxy-5,5-dimethyl-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridin-2-yl}acetyl}urea	HCID 44327286	—
Product	{{8-[5-(4-Fluorophenyl)-2-pentyl]-5,5-dimethyl-10-(4-morpholinobutyryloxy)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridin-2-yl}acetyl}urea hydrochloride	HCID 70607348	—

Reaction Steps

The above-titled compound was prepared according to the method of Example 8 by reacting equimolar quantities of {{8-[5-(4-fluorophenyl)-2-pentyl]-10-hydroxy-5,5-dimethyl-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridin-2-yl}acetyl}urea and 4-morpholinobutyric acid hydrochloride in the presence of dicyclohexylcarbodiimide.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04172943
Source dataset	uspto-grants-1979_10
ORD ID	ord-d0d7f9618e934b80a7c42fc6237fd214
Source note	uspto-grants-1979_10