HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Bromosuccinamide → 2,7-Dibromo-4-methoxybenzo[d]thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Bromosuccinamide | HCID 9834204 | — |
| Reactant | 2-Bromo-4-methoxy-1,3-benzothiazole | HCID 18356997 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2,7-Dibromo-4-methoxybenzo[d]thiazole | HCID 18356994 | 119.4% |
Reaction Steps
Starting from 2-bromo-4-methoxybenzothiazole (1.6 g), N-bromosuccinamide (0.91 g) and acetonitrile (100 ml). Purification by flash chromatography (eluent 20% ethylacetate/hexane) yielded the title compound as an off-white solid (1.8 g). TLC Rf 0.31 (20% ethyl acetate in heptane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313116B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-950237d0a2f64321b1fcd2e90aa0eea7 |
| Source note | uspto-grants-2001_11 |