HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → HCID 28165295, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Boc-L-Valine | HCID 83693 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 28165295 | HCID 28165295 | — |
Reaction Steps
In a DMF solution containing 2.0 g of Boc-Val-OH, 0.92 ml of isobutylamine, 1.40 g of HOBt and 2.28 g of DCC were added under ice cooling and the resultant mixture was stirred for 14 hr. The reaction mixture was treated similarly to that in Example 51 (Process 1) to give 1.89 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313094B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-ae17d9a5403d4cada7cfb0e46a1a1284 |
| Source note | uspto-grants-2001_11 |