HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → (2-Isopropyl-6-methylphenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 2-Isopropyl-6-methylbenzaldehyde | HCID 12467047 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2-Isopropyl-6-methylphenyl)methanol | HCID 18357444 | 98% |
Reaction Steps
To a solution of 2-isopropyl-6-methylbenzaldehyd (1.75 g, 10.8 mmol) in methanol (15 ml) was added sodium borohydride (0.35 g, 9.5 mmol) and the mixture was stirred 1 h. at room temperature. The solvent was evaporated under reduced pressure and to the residue was added hexane and water. The organic layer was separated and evaporated under reduced pressure to give 1.73 g (98%) of the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313137B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-e446b94faa7448ce83e2e8534874030c |
| Source note | uspto-grants-2001_11 |