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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 427636Generated: October 30, 2026

4-tert-Butylbenzoyl chloride → 2-[(4-tert-Butylbenzoyl)amino]-N-(4-methoxyphenyl)-6-fluorobenzamide

https://huagongshe.com/reaction/427636

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-tert-Butylbenzoyl chlorideHCID 74372—
ReactantN-(4-methoxyphenyl)-2-amino-6-fluorobenzamideHCID 18174595—
Product2-[(4-tert-Butylbenzoyl)amino]-N-(4-methoxyphenyl)-6-fluorobenzamideHCID 1817441966.3%

Reaction Steps

Using the procedure described in Example 93, Part A, N-(4-methoxyphenyl)-2-amino-6-fluorobenzamide (1.9 mmol) and 4-tert-butylbenzoyl chloride (2.1 mmol) yielded 530 mg (65%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06313122B1
Source datasetuspto-grants-2001_11
ORD IDord-425416633d9b4f2fa73b8b51884a9814
Source noteuspto-grants-2001_11