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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 427738Generated: October 30, 2026

5-Bromoindoline → 5-Bromo-1-[2-(pyridin-2-ylmethyloxy)pyridin-5-ylcarbamoyl]-indoline

https://huagongshe.com/reaction/427738

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromoindolineHCID 3411566—
ReactantPhenyl N-[2-(pyridin-2-ylmethyloxy)pyridin-5-yl]carbamateHCID 11141770—
Product5-Bromo-1-[2-(pyridin-2-ylmethyloxy)pyridin-5-ylcarbamoyl]-indolineHCID 18357723—

Reaction Steps

Phenyl N-[2-(pyridin-2-ylmethyloxy)pyridin-5-yl]carbamate (D3) and 5-bromoindoline were converted into the title compound using a method similar to that of Example 1, m.p. 138-139° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06313145B1
Source datasetuspto-grants-2001_11
ORD IDord-b742c408adf44ec58e4fd583a05b8d71
Source noteuspto-grants-2001_11