反应详情

To a solution of 4-(2-aminophenylamino)benzophenone (compound 101, 0.58 g, 2 mmol) and hydroxylamine hydrochloride (0.42 g, 6 mmol) in ethanol (30 ml) was added sodium acetate (0.49 g, 6 mmol). The reaction mixture was refluxed for 30 hours, cooled to room temperature, filtered, and evaporated in vacuo. The residue was treated with water (10 ml) and diluted ammonium hydroxide (5 ml). The precipitate that forms was filtered off, washed with water and dried to afford the title compound.

1. temperatureThe reaction mixture was refluxed for 30 hours
2. filtrationfiltered
3. customevaporated in vacuo
4. additionThe residue was treated with water (10 ml) and diluted ammonium hydroxide (5 ml)
5. filtrationThe precipitate that forms was filtered off
6. washwashed with water
7. customdried