Ethyl formate → HCID 18358182, compound

HRID 428301Notes

Reaction equation

HRID 428301 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9]1[CH:22]=[CH:21][C:12]([C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:14])=[CH:11][CH:10]=1.[CH:23](OCC)=[O:24]>>[C:13]([C:12]1[CH:21]=[CH:22][C:9]([NH:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH:1][CH:23]=[O:24])=[CH:10][CH:11]=1)(=[O:14])[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 8025Ethyl formateHCID 11737779{4-[(2-Aminophenyl)amino]phenyl}(Phenyl)methanone2×

Product 1

HCID 18358182HCID 18358182, compound

Procedure

A solution of 4-(2-aminophenylamino)benzophenone (Compound 101 0.29 g, 1.0 mmol) in ethyl formate (5.0 ml, 63 mmol) was refluxed for 16 hours. The reaction mixture was evaporated in vacuo and dissolved i ethyl acetate. The solution was filtered and evaporated in vacuo. The residue was crystallized on the addition of diethyl ether to afford the pure title compound.

Workup

  1. customThe reaction mixture was evaporated in vacuo
  2. dissolutiondissolved i ethyl acetate
  3. filtrationThe solution was filtered
  4. customevaporated in vacuo
  5. customThe residue was crystallized on the addition of diethyl ether

Sources & evidence

ORD record
ord-55b69237776d4723be333710f7eb31b5
Source dataset
uspto-grants-2001_11
Patent number
US06313174B1

Reaction notes

Loading…