化工社化工社 化学情報印刷レポート · 研究参考用
6-Fluoroindole → 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-6-fluoro-1H-indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Fluoroindole | HCID 351278 | — |
| 反応物 | 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole | HCID 2763857 | — |
| 生成物 | 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-6-fluoro-1H-indole | HCID 18414166 | 96.3% |
反応手順
This compound was prepared in the manner described for intermediate 1a by replacing indole with 6-fluoroindole (5.14 g, 38 mmol) ) to afford 10 g (96.3%) of the title compound as a white solid: mp 196-197° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06313126B1 |
| 出典データセット | uspto-grants-2001_11 |
| ORD ID | ord-073920222edc4c1988928536db1edb8e |
| 出典メモ | uspto-grants-2001_11 |