HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1H-Indol-3-YL)cyclohexanone → 4-(1H-Pyrrolo[2,3-B]pyridin-3-YL)cyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1H-Indol-3-YL)cyclohexanone | HCID 10846264 | — |
| Reactant | HCID 178419917 | HCID 178419917 | — |
| Product | 4-(1H-Pyrrolo[2,3-B]pyridin-3-YL)cyclohexanone | HCID 18414106 | 95% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 3a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-1H-indole with 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-1H-azaindole (2.48 g) to afford 1.96 g (95%) of the title compound as a white solid: mp 162-164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313126B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-f8361e3bad294f1fa893a17f8e730bd4 |
| Source note | uspto-grants-2001_11 |