HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1H-Indol-3-YL)cyclohexanone → 4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-cyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1H-Indol-3-YL)cyclohexanone | HCID 10846264 | — |
| Reactant | 1-(2-Methoxy-phenyl)4-(1,4-dioxa-spiro[4,5]dec-8-yl)-piperazine | HCID 11002098 | — |
| Product | 4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-cyclohexanone | HCID 10565307 | 93% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 3a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-1H-indole with 1-(2-methoxy-phenyl)-4-(1,4-dioxa-spiro[4,5]dec-8-yl)-piperazine (5.0 g, 15 mmol) to afford 4.0 g (93%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313126B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-6654b02fe8db4c36ae2ab466c091fc0d |
| Source note | uspto-grants-2001_11 |