4-Toluenesulfonyl chloride → HCID 86583596, compound

HRID 428589Notes

Reaction equation

HRID 428589 reaction equation
[CH2:1]([N:8]1[CH2:12][CH2:11][C@H:10]([OH:13])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:14]1([CH3:24])[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[CH2:1]([N:8]1[CH2:12][CH2:11][C@H:10]([OH:13])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1.[S:20]([C:17]1[CH:18]=[CH:19][C:14]([CH3:24])=[CH:15][CH:16]=1)([O-:13])(=[O:22])=[O:21]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 2733875(S)-(-)-1-Benzyl-3-pyrrolidinol

Product 1

HCID 86583596HCID 86583596, compoundYield 98%

Procedure

This was prepared from (S)-1-benzyl-3-pyrrolidinol and p-toluenesulfonyl chloride in 98% yield according to the procedures similar to those described in Preparation 24.

Workup

  1. customthose described in Preparation 24

Sources & evidence

ORD record
ord-680bc662ea0647c39d875dac947779cb
Source dataset
uspto-grants-2001_11
Patent number
US06313302B2

Reaction notes

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