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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 428609Generated: October 29, 2026

HCID 53998100, compound → HCID 178467693, compound

https://huagongshe.com/reaction/428609

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53998100HCID 53998100—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 178467693HCID 178467693—

Reaction Steps

3.3 g of 2-(3-benzyl-3H-imidazol-4-yl)-4-phenylbutan-2-ol is dissolved in 100 ml of ethanol. The reaction solution is hydrogenated at 50° C. with 10% palladium on carbon as catalyst for 4.5 hours. Work-up of the reaction mixture gives the crude product, which is recrystallized from ethyl acetate. The yield is 2.0 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06313311B1
Source datasetuspto-grants-2001_11
ORD IDord-8192b4dface748fc8d0622e2a3357103
Source noteuspto-grants-2001_11