Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 178486576 | HCID 178486576 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178466014 | HCID 178466014 | — |
Reaction Steps
3-(1H-imidazol-4-yl)-5-methoxy-6,7-dimethylindan-1-ol (cis-isomer, 0.1 g) is dissolved in the mixture of ethanol (20 ml) and concentrated hydrochloric acid (2 ml). The solution is stirred at 25° C. for one hour. Work-up of the reaction mixture gives the crude product, which is purified by flash chromatography using methylene chloride-methanol as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06313311B1 |
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| Source dataset | uspto-grants-2001_11 |
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| ORD ID | ord-c36feb504b8a4257a74929483c6ccdd0 |
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| Source note | uspto-grants-2001_11 |
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