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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 428621Generated: October 25, 2026

Ethanol → HCID 178466014, compound

https://huagongshe.com/reaction/428621

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantHCID 178486576HCID 178486576—
SolventHydrochloric AcidHCID 313—
ProductHCID 178466014HCID 178466014—

Reaction Conditions

Temperature25 °C

Reaction Steps

3-(1H-imidazol-4-yl)-5-methoxy-6,7-dimethylindan-1-ol (cis-isomer, 0.1 g) is dissolved in the mixture of ethanol (20 ml) and concentrated hydrochloric acid (2 ml). The solution is stirred at 25° C. for one hour. Work-up of the reaction mixture gives the crude product, which is purified by flash chromatography using methylene chloride-methanol as eluent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06313311B1
Source datasetuspto-grants-2001_11
ORD IDord-c36feb504b8a4257a74929483c6ccdd0
Source noteuspto-grants-2001_11