HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 2,5-Difluoroanisole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,5-Difluorophenol | HCID 94952 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,5-Difluoroanisole | HCID 2724989 | — |
Reaction Steps
35.0 g of the product of Step A, 350 ml of acetone, 44.6 g of potassium carbonate and 40.7 g of dimethyl sulfate (neutralized on potassium bicarbonte) and was allowed to return to ambient temperature. Water was added and extraction was carried out with ether. The extracts were washed, dried and concentrated to dryness under reduced pressure to obtain 39.8 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313305B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-85bf43347afd4681b4f09c3276b2b80c |
| Source note | uspto-grants-2001_11 |