反应详情

温度

40 °C

To a solution of methyl 2-phenylbenzoxazole-4-carboxylate (0.02 g; 0.0905 mmol) in methanol (3 ml) was added aqueous ammonia (3 ml). This was warmed to 40° C. and left to stir, whilst the reaction was monitored by TLC (1:4 EtOAc:petrol). Once all the starting material had reacted a white precipitate was formed. The solvent was removed to yield a white solid, which was recrystallised from ethyl acetate and petrol (70%).

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2. customOnce all the starting material had reacted a white precipitate
3. customwas formed
4. customThe solvent was removed
5. customto yield a white solid, which
6. customwas recrystallised from ethyl acetate and petrol (70%)