HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylpiperidine → 1-{3-[(4'-{[(2R,5R)-2,5-dimethylpyrrolidinyl]carbonyl}[1,1'-biphenyl]-4-yl)oxy]propyl}-4-methylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylpiperidine | HCID 69381 | — |
| Reactant | (2R,5R)-1-{[4'-(3-chloropropoxy)[1,1'-biphenyl]-4-yl]carbonyl}-2,5-dimethylpyrrolidine | HCID 70141087 | — |
| Product | 1-{3-[(4'-{[(2R,5R)-2,5-dimethylpyrrolidinyl]carbonyl}[1,1'-biphenyl]-4-yl)oxy]propyl}-4-methylpiperidine | HCID 70141170 | — |
Reaction Steps
The product from Example 4A and 4-methylpiperidine were processed as described in Example 10F to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316475B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-5101e155b2844d7288bc83d28807390c |
| Source note | uspto-grants-2001_11 |