HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 178434553, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide | HCID 53424263 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178434553 | HCID 178434553 | 33.6% |
Reaction Steps
N-[4-(Trifluoromethyl)phenyl]-2-(ethoxymethylene)acetoacetamide (1 g) in 3 mL of ethanol is stirred overnight with 0.3 g of hydrazine hydrate. The precipitate is collected by vacuum filtration, washed with ethanol:water 2:1 and dried to give 0.3 g of 3-methyl-4-[4-(trifluoromethyl)phenylaminocarbonyl]pyrazole as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316479B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-97af3a390b1c41d88dd2e5f11f294d31 |
| Source note | uspto-grants-2001_11 |