Sulfuric Acid → HCID 18355456, compound

HRID 429338Notes

Reaction equation

HRID 429338 reaction equation
[I:1][C:2]1[CH:3]=[C:4]([CH:21]=[C:22]([I:25])[C:23]=1[OH:24])[C:5]([C:7]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[O:9][C:8]=1[CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[O:6].S(=O)(=O)(O)O>CC(O)CC>[I:25][C:22]1[CH:21]=[C:4]([CH:3]=[C:2]([I:1])[C:23]=1[OH:24])[C:5]([C:7]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[O:9][C:8]=1[CH2:16][CH2:17][C:18]([O:20][CH:2]([CH2:23][CH3:22])[CH3:3])=[O:19])=[O:6]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 18355455HCID 18355455, compound

Product 1

HCID 18355456HCID 18355456, compound

Reagents, catalysts & solvents 1

HCID 6568(+-)-2-ButanolSolvent

Procedure

562 g of compound 6 are stirred at 85° C. in 900 g of 2-butanol and 50 ml of sulfuric acid for 5 hours. Cool down to room temperature. Filter the product. Wash twice with 100 ml of hexane.

Workup

  1. filtrationFilter the product
  2. washWash twice with 100 ml of hexane

Sources & evidence

ORD record
ord-87124c601c74420697bc1fa235218325
Source dataset
uspto-grants-2001_11
Patent number
US06316487B1

Reaction notes

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