HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-(diethylamine)ethane hydrochloride → HCID 10212316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-(diethylamine)ethane hydrochloride | HCID 13363 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 18355456 | HCID 18355456 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10212316 | HCID 10212316 | — |
Reaction Steps
619 g of compound 7 and 180 g of diethylaminoethyl chloride, hydrochloride salt, are dissolved in 2L of methylene chloride and 500 ml of water. To this add 23 g of benzyltriethylammonium chloride and 80 g of sodium hydroxide in 2L of water. Stir vigorously for 5 hours. Keep the organic phase. Wash with 1 L of water. Dry over sodium sulfate. Filter. Evaporate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316487B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-0cc6024e745a4b90bb1bdda087cd3c9e |
| Source note | uspto-grants-2001_11 |